Papers - Chronologically 

  1. Kejlova, K., Vlkova, A., Jirova, D., Dvorakova,  M., Svobodova, L., Kandarova, H., Letasiova, S/. Kolarova, H., Heinonen, T., Mannerstrom M.,(2020). Evaluation of the toxicity profiles of rare earth elements salts (lanthanides). Accepted for publication. 

  2. Líšková, A., Letašiová, S., Jantová, S., Brezová, V., Kandárová, H. (2020). Evaluation of phototoxic and cytotoxic potential of TiO2 nanosheets in 3D reconstructed human skin model. Accepted for Publication. 

  3. Ilaria Pulsoni, Jan Markus, Seyoum Ayehunie, Silvia Scaglione, Helena Kandarova, Maurizio Aiello (2020). Sviluppo e validazione di una piattaforma innovativa per lo studio in vitro dei diversi meccanismi di assorbimento intestinale -   Dispositivo fluidico multi-camera (MIVO®) con inserti di tessuto 3D. L’Integratore Nutrizionale - Ricerca  I ennovazione. Ahead of Print. 

  4. Marrella, A., Buratti, P., Markus, J., Firpo, G., Pesenti, M., Landry, T., Ayehunie, S., Scaglione, S., Kandarova, H. and Aiello, M. (2020). In vitro demonstration of intestinal absorption mechanisms of different sugars using 3D organotypic tissues in a fluidic device. In ALTEX - Alternatives to Animal Experimentation, 2020, vol. 37, [Epub ahead of print]. ISSN 1868-596X. Typ: ADMA

  5. Kandarova H., Jírová D. (2019). Behind the claim -  In Vitro 3D human tissue models in the studies of cosmetics for “sensitive skin”. H&PC Today - Household and Personal Care Today - vol. 14(2) March/April 2019.

  6. Vinken M., Suter-Dick L., Kandarova H. (2019). ESTIV2018: 20th anniversary of the International Congress on In Vitro Toxicology. Toxicology in Vitro. Jun 18; 60:293-295. doi: 10.1016/j.tiv.2019.06.005

  7. Kejlova K., Dvorakova M., Vavrous A., Sevcik V., Kandarova H., Letasiova S., Sosnovcova J., Jirova D. (2019). Toxicity of food contact paper evaluated by combined biological and chemical methods. Toxicology in Vitro, Sep; 59:26-34. doi: 10.1016/j.tiv.2019.04.001

  8. Coleman K.P., Grailer T.P., McNamara L.R., Rollins B.L., Christiano N.J., Kandarova H., De Jong W.H.(2018). Preparation of irritant polymer samples for an in vitro round robin study, Toxicology in Vitro, 02 Feb 2018, 50:401-406. DOI: 10.1016/j.tiv.2018.01.018

  9. Kandarova H., Bendova H., Letasiova S., Coleman K.P., De Jong W.H., Jirova D.(2018). Evaluation of the medical devices benchmark materials in the controlled human patch testing and in the RhE in vitro skin irritation protocol, Toxicology in Vitro, 50

  10. Kandarova H., Willoughby J.A., De Jong W.H., Letasiova S., Milasova T., Bachelor M.A., Breyfogle B., Handa Y., De la Fonteyne L., Coleman K.P. (2018). Pre-validation of an in vitro skin irritation test for medical devices using the reconstructed human tissue model EpiDerm™, Toxicology in Vitro, 50

  11. De Jong W.H., Hoffmann S., Lee M., Kandarova H., Pellevoisin C., Haishima Y., Rollins B., Zdawczyk A., Willoughby J., Bachelor M., Schatz T., Skoog S., Parker S., Sawyer A., Pescio P., Fant K., Kim K.(2018). Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts. Toxicology in Vitro, 50

  12. Adriaens E., Alepee N., Kandarova H., Drzewieckac A., Gruszka K., Guest R., Willoughby J.A., Verstraelen S., Van Rompay A.R. (2018). Reprint of “CON4EI: Selection of the reference chemicals for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro, 49

  13. Verstraelen S., Maglennon G., Hollanders K., Boonen F., Adriaens E., Alepee N., Drzewiecka A., Gruszka K., Kandarova H., Willoughby J.A., Guest R., Schofield J., Van Rompay A.R.(2018). Reprint of “CON4EI: Bovine Corneal Opacity and Permeability (BCOP) test for hazard identification and labelling of eye irritating chemicals”. Toxicology in Vitro, 49

  14. Adriaens E., Verstraelen S., Alepee N., Kandarova H., Drzewiecka A., Gruszka K., Guest R., Willoughby J.A., Van Rompay A.R.(2018). CON4EI: Development of testing strategies for hazard identification and labelling for serious eye damage and eye irritation of chemicals. Toxicology in Vitro, 49

  15. Geerts L., Adriaens E., Alepee N., Guest R., Willoughby J.A., Kandarova H., Drzewiecka A., Fochtman P., Verstraelen S., Van Rompay A.R.(2018). CON4EI: Evaluation of QSAR models for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro, 49

  16. Kandarova H., Letasiova S., Adriaens E., Guest R., Willoughby J.A., Drzewiecka A., Gruszka K., Alepee N., Verstraelen S., Van Rompay A.R.(2018). CON4EI: CONsortium for in vitro Eye Irritation testing strategy - EpiOcular™ time-to-toxicity (EpiOcular ET-50) protocols for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro, 49

  17. Adriaens E., Willoughby J.A., Meyer B.R., Blakeman L.C., Alepee N., Fochtman P., Guest R., Kandarova H., Verstraelen S., Van Rompay A.R.(2018). CON4EI: Short Time Exposure (STE) test method for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro, 49

  18. Adriaens E., Guest R., Willoughby J.A., Fochtman P., Kandarova H., Verstraelen S., Van Rompay A.R.(2018). CON4EI: Slug Mucosal Irritation (SMI) test method for hazard identification and labelling of serious eye damaging and eye irritating chemicals

  19. Kandarova H., Letasiova S., Adriaens E., Guest R., Willoughby J.A., Drzewiecka A., Gruszka K., Alepee N., Verstraelen S., Van Rompay A.R.(2018). CON4EI: EpiOcular™ Eye Irritation Test (EpiOcular™ EIT) for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro, 49

  20. Van Rompay A.R., Alepee N., Nardelli L., Hollanders K., Leblanc V., Drzewiecka A., Gruszka K., Guest R., Kandarova H., Willoughby J.A., Verstraelen S., Adriaens E.(2018). CON4EI: SkinEthic™ Human Corneal Epithelium Eye Irritation Test (SkinEthic™ HCE EIT) for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro, 49

  21. Kandarova, H. and Iscan, M. (2017) 53rd EUROTOX Congress: Connecting for a Safer Future. EUROTOX 2017 Supplement, Foreword. Toxicol Lett. 2017 Oct 20; 280 Suppl 1:S1. doi: 10.1016/j.toxlet.2017.08.001. Epub 2017 Aug 8.

  22. Verstraelen S., Maglennon G., Hollanders K., Boonen F., Adriaens E., Alepee N., Drzewiecka A., Gruszka K., Kandarova H., Willoughby J.A., Guest R., Schofield J., Van Rompay A.R.(2017). CON4EI: Bovine Corneal Opacity and Permeability (BCOP) test for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro 44. 

  23. Adriaens E., Alepee N., Kandarova H., Drzewieckac A., Gruszka K., Guest R., Willoughby J.A., Verstraelen S., Van Rompay A.R.(2017). CON4EI: Selection of the reference chemicals for hazard identification and labelling of eye irritating chemicals. Toxicology in Vitro 44. 

  24. Desprez B., Barroso J., Griesinger C., Kandárová H., Alépée N., Fuchs H.W (2015). Two novel prediction models improve predictions of skin corrosive sub-categories by test methods of OECD Test Guideline No. 431, Toxicology in Vitro, Volume 29, Issue 8, December 2015, Pages 2055-2080,

  25. Sarah Gordon, Mardas Daneshian, Joke Bouwstra, Francesca Caloni, Samuel Constant, Donna E Davies, Gudrun Dandekar, Carlos A Guzman, E Fabian, Eleonore Haltner, Thomas Hartung, Nina Hasiwa, P Hayden, H Kandarova, S Khare, HF Krug, C Kneuer, Marcel Leist, G Lian, U Marx, Marco Metzger, K Ott, P Prieto, MS Roberts, EL Roggen, T Tralau, C van den Braak, Heike Walles, Claus-Michael Lehr (2015). Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.Altex,32,4,327-378.

  26. Hayden, Patrick J; Bachelor, Michael; Ayehunie, Seyoum; Letasiova, Silvia; Kaluzhny, Yulia; Klausner, Mitchell; Kandárová, Helena (2015). Application of MatTek In Vitro Reconstructed Human Skin Models for Safety, Efficacy Screening, and Basic Preclinical Research.  Applied In Vitro Toxicology,1,3,226-233,2015, Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA"

  27. Kaluzhny, Y., Kandárová, H., Handa, Y., DeLuca, J., Truong, T., Hunter, A., Kearney, P., d'Argembeau-Thornton, L., Klausner, M. (2015). The EpiOcular Eye Irritation Test (EIT) for hazard identification and labelling of eye irritating chemicals: protocol optimisation for solid materials and the results after extended shipment.  Alternatives to Laboratory Animals : ATLA [2015, 43(2):101-127] 

  28. Sarah Gordon, Mardas Daneshian, Joke Bouwstra, Francesca Caloni, Samuel Constant, Donna E Davies, Gudrun Dandekar, Carlos A Guzman, E Fabian, Eleonore Haltner, Thomas Hartung, Nina Hasiwa, P Hayden, H Kandarova, S Khare, HF Krug, C Kneuer, Marcel Leist, G Lian, U Marx, Marco Metzger, K Ott, P Prieto, MS Roberts, EL Roggen, T Tralau, C van den Braak, Heike Walles, Claus-Michael Lehr (2015). Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.Altex,32,4,327-378.

  29. Kaluzhny, Y., Kandárová, H., d'Argembeau-Thornton, L., Kearney, P., Klausner, M. (2015). Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model. JoVE (Journal of Visualized Experiments), 102, 2015 

  30. Basketter, D., Jirova, D., Kandarova, H (2012). Review of skin irritation/corrosion Hazards on the basis of human data: A regulatory perspective. Interdisciplinary toxicology 06/2012; 5(2):98-104.

  31. Ceridono, M., Tellner,P., Bauer, D., Barroso,J., Alépée,N., Corvi, R., De Smedt,A., Fellows,M.D., Gibbs,N.K. Heisler, E., Kandarova, H. [......] and Wilcox, J. (2012). The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop. Regulatory Toxicology and Pharmacology; 63(3):480-8.

  32. Kolle, S.N., Kandárová, H., Wareing, B., van Ravenzwaay, B.,  Landsiedel, R. (2011). In-house validation of the EpiOcular(TM) eye irritation test and its combination with the bovine corneal opacity and permeability test for the assessment of ocular irritation. ATLA, 39 (4), 365-387.

  33. Kaluzhny, Y., Kandárová, H., Hayden, P. Kubilus, J., d'Argembeau-Thornton, L., Klausner, M. (2011). Development of the EpiOcular(TM) eye irritation test for hazard identification and labelling of eye irritating chemicals in response to the requirements of the EU cosmetics directive and REACH legislation. ATLA, 39 (4), 339-364.

  34. Kandárová, H., Letasiová, S. (2011). Alternative methods in toxicology: pre-validated and validated methods. Interdiscip Toxicol, 4 (3), 107-113. 

  35. Kandárová, H., Kaluzhny, Y., Klausner, M., Hayden, P. (2010). The Way Forward for In Vitro Skin Irritation and Corrosion Testing–2010 Update. AltTOX.org. E-publication:  http://alttox.org/the-way-forward-for-in-vitro-skin-irritation-and-corrosion-testing-2010-update/ Published: December 17, 2010 

  36. Jirova, D., Basketter, D., Liebsch, M., Bendova, H., Kejlova, K, Marriott, M., Kanďárová H. (2010) Comparison of Human Skin Irritation Patch Test Data with In Vitro Skin Irritation Assays and Animal Data. Contact Dermatitis 62 (2), pp. 109 -116.

  37. Kandárová H., Hayden, P., Klausner, M., Kubilus, J., Kearney, P. and Sheasgreen, J. (2009): In Vitro Skin Irritation Test: Improving the Sensitivity of the EpiDerm Skin Irritation Test Protocol. ATLA  37 (6), pp. 671 – 669.

  38. Kandárová H., Hayden, P., Klausner, M., Kubilus, J., Sheasgreen, J. (2009). An In Vitro Skin Irritation Test (SIT) using the EpiDerm Reconstructed Human Epidermal (RHE) Model. JoVE. 29. http://www.jove.com/index/details.stp?id=1366, doi: 10.3791/1366.  

  39. Jírová, D., Liebsch. M., Basketter, D., Kandárová, H., Bendová, H., Marriott, M., Kejlová, K., Spiller, E. (2008)  Comparison of human skin irritation and photo-irritation patch test data with cellular in vitro assays and animal in vivo data. Alternatives to Animal Testing and Experimentation - AATEX 14. 359–365.  

  40. Spielmann, H., Hoffmann, S., Liebsch, M., Botham, P., Fentem, J., Eskes, C., Rouguet, R., Cotovio, J., Cole, T., Worth, A., Heyling, J., Jones, P., Robles, C., Kandárová, H., Gamer, A., Remmele, M., Curren, R., Raabe, H., Cockshott, A., Gerner, I. and Zuang, V. (2007). The ECVAM International Validation Study on In Vitro Tests for Acute Skin Irritation: Report on the Validity of the EPISKIN and EpiDerm Assays and on the Skin Integrity Function Test. ATLA 35, 559–601

  41. Kejlová, K., Jírová, D., Bendová, H., Kandárová, H., Weidenhoffer Z., Kolářová, H. and Liebsch M (2007). Phototoxicity of Bergamot oil assessed by in vitro techniques in combination with human patch tests. Toxicology in Vitro 21, p. 1298–1303.

  42. Kanďárová, H., Liebsch, M., Schmidt, E., Traue, D., Spielmann, H., Meyer, K., Steinhoff, C., Tornier, C., De Wever, B., Rosdy, M., (2006). Assessment of the skin irritation potential of chemicals using the SkinEthic RHE and the “common skin irritation protocol” evaluated in the ECVAM Skin irritation validation study. ATLA 34, 393–406.

  43. Kanďárová, H., Liebsch, M., Spielmann, H., Genschow, E., Schmidt, E., Guest, R., Whittingham, A., Warren, N., Gamer, A., Remmele, M., Kaufmann, T., Wittmer, E., De Wever, B., Rosdy, M., (2006). Assessment of the SkinEthic Reconstituted Human Epidermis for skin corrosion testing according to OECD guideline 431. Toxicology in Vitro 20, 547–559.

  44. Kandárová, H., Richter, H. Liebsch, M. and Lademann J. (2007): Stratum corneum architecture of reconstructed human skin models monitored by fluorescent confocal laser scanning microscopy. Laser Phys. Lett. Volume 4/4, Pages 308 – 311.

  45. Kanďárová, H., Liebsch, M.,  Gerner, I., Schmidt, E., Genschow, E., Traue, D.,  Spielmann, H., (2005). EpiDerm Skin Irritation Test Protocol – Assessment of the performance of the optimised test. ATLA 33 (4), p. 351

  46. Schreiber, S., Mahmoud, A., Vuia, A., Rübbelke, M.K., Schmidt, E., Schaller, M., Kandárová, H., Haberland, A., Schäfer, U.F., Bock, U., Korting, H.C., Liebsch, M. and Schäfer-Korting, M., (2005). Reconstructed Epidermis versus Human and Animal Skin in Skin Absorption Studies Toxicology in Vitro, 19 (6), p.813-822.

  47. Kanďárová, H., Liebsch, M., Genschow, E., Ingrid, Gerner, Traue, D., Slawik, B., Spielmann, H., (2004). Optimisation of the EpiDerm Test Protocol for the upcoming ECVAM Validation Study on In Vitro Skin Irritation Tests. ALTEX 21, 3/04, 107-114. 

  48. Kandárová, H., Jantová, S., Hojerová, J., (2004). New approaches to the safety evaluation of cosmetic products and ingredients. Review. Česko - Slovenská dermatologie 79 (2), p. 75-83 (Indexed/Excerpted in Bibliographia Medica Čechoslovaca, EMBASE/Excerpta Medica, Biological Abstracts, Chemical Abstracts). 

  49. Kandárová, H., Hojerová, J., Jantová, S., (2002): Safety of Cosmetic products - In vitro methods. Derma 4, p.15-17  

Editor of Special Editions 

  1. Vingaard A., Blaauboer B., Kandarova H. (2021). “Proceedings of the 21th ESTIV congress 2020”.Toxicology In Vitro 

  2. Vinken M., Suter-Dick L., Kandarova H. (2019) “Proceedings of the 20th ESTIV congress 2018”. Toxicology In Vitro 60.

  3. Kandarova, H. and Iscan, M. (2017) 53rd EUROTOX Congress: Connecting for a Safer Future. EUROTOX 2017 Supplement,  Toxicol Lett. 2017 Oct 20; 280 Suppl 1:S1

  4. Jana Navarová, Helena Kanďárová, Mojmír Mach (2014). Connecting for safer Europe : 19th Interdisciplinary toxicological conference. Programme & abstracts.Interdisciplinary toxicology 7 (S1) 

  5. Jana Navarová, Helena Kanďárová, Mojmír Mach (2012). TOXCON 2012. Toxicology at the crossrodad : 17th Intedisciplinary toxicological conference and Advanced toxicological course. The High Tatras, Slovakia. Stará Lesná - hotel Academia, August 27-31, 2012. Programme and abstracts. Interdisciplinary Toxicology 5 (S1)

  6. Mojmír Mach, Helena Kanďárová, Jana Navarová, Eduard Ujhazy, Michal Dubovický (2010). TOXCON 2010: Borderless toxicology. 15th Interdisciplinary toxicological conference & advanced toxicological course. The High Tatras Slovakia, Stará Lesná - Hotel Academia, September 6-10, 2010. Interdisciplinary toxicology 3 (1). 1337-6853 

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